Genome MuSiC v0.4

The Mutational Significance In Cancer (MuSiC) suite of tools consists of downstream analysis tools that can:

  • Apply statistical methods to identify significantly mutated genes
  • Highlight significantly altered pathways
  • Investigate the proximity of amino acid mutations in the same gene
  • Search for gene-based or site-based correlations to mutations and relationships between mutations themselves
  • Correlate mutations to clinical features, using typical correlation measures, and generalized linear models
  • Cross-reference findings with relevant databases such as Pfam, COSMIC, and OMIM
  • Generate typical visualizations like Kaplan-Meier survival estimates, and mutation status matrices

The MuSiC suite is a set of tools aimed at discovering the significance of somatic mutations found within a given cohort of cancer samples, and with respect to a variety of external data sources.

Accessing the software

To load the module:

$ module load apps/genome-music/v0.4

An example command to include in your job script:

genome music proximity mutation-list

Accessing Previous Versions

Wherever possible, previous versions of this application will be retained for continuity, especially for research projects that require a consistent version of the software throughout the project. Such versions, however, may be unsupported by IT Services or the applications vendor, and may be withdrawn at short or no notice if they can no longer run on the cluster - for example, essential operating system upgrades may be incompatible with old versions.

At present there are no previous versions of this application on the BlueBEAR service.

Known Problems & Limitations


Other Information

The Support Level for this application is An.

Visit the Genome MuSiC website for more information regarding this application.

Last modified: 23 November 2017